Skin cancer is the out-of-control growth of abnormal cells in the epidermis, the outermost skin layer, caused by unrepaired DNA damage that triggers mutations. These mutations lead the skin cells to multiply rapidly and form malignant tumors.
What type of tissue is affected by melanoma?
It can easily spread into deep layers of skin as well as to lymph nodes and other organs. The skin’s layers include the epidermis (outer layer), dermis (inner layer) and hypodermis (subcutaneous tissue). Melanoma typically develops in the epidermis, which contains melanocytes.
What part of the integumentary system does skin cancer affect?
Squamous cell carcinoma is a cancer that affects the keratinocytes of the stratum spinosum and presents as lesions commonly found on the scalp, ears, and hands (Figure 2). It is the second most common skin cancer.
What layer of skin does basal cell carcinoma affect?
About 8 out of 10 skin cancers are basal cell carcinomas (also called basal cell cancers). These cancers start in the basal cell layer, which is the lower part of the epidermis. These cancers usually develop on sun-exposed areas, especially the face, head, and neck. They tend to grow slowly.
What’s the difference between basal cell carcinoma and melanoma?
Melanoma typically begins as a mole and can occur anywhere on the body. Squamous cell carcinoma may appear as a firm red bump, a scaly patch, or open sore, or a wart that may crust or bleed easily. Basal cell carcinoma may appear as a small white or flesh-colored bump that grows slowly and may bleed.
What type of tissue does squamous cell carcinoma affect?
Squamous cell skin cancer affects the epidermis, the top layer of skin. Squamous cell cancer may occur in undamaged skin. It can also occur in skin that has been injured or inflamed. Most squamous cell cancers occur on skin that is regularly exposed to sunlight or other ultraviolet radiation.
Which of the following is the main tissue in the dermis?
The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain.
How does skin cancer affect the skin?
Skin cancer usually appears as a growth that changes in color, shape, or size. This can be a sore that does not heal or a change in a mole or skin growth. These changes usually happen in areas that get the most sun—your head, neck, back, chest, or shoulders.
What layer of epidermis is squamous cell carcinoma?
Squamous cell skin cancer also develops from keratinocytes in the epidermis. This is also called squamous cell carcinoma (SCC). These cancers develop in the cell layer just above the basal layer. Melanoma skin cancer starts in the skin cells called melanocytes.
What cells are affected in basal cell carcinoma?
Basal cell carcinoma occurs when one of the skin’s basal cells develops a mutation in its DNA. Basal cells are found at the bottom of the epidermis — the outermost layer of skin. Basal cells produce new skin cells.
What BCC looks like?
What does BCC look like? BCCs can look like open sores, red patches, pink growths, shiny bumps, scars or growths with slightly elevated, rolled edges and/or a central indentation. At times, BCCs may ooze, crust, itch or bleed. The lesions commonly arise in sun-exposed areas of the body.
What is worse basal cell or squamous?
Though not as common as basal cell (about one million new cases a year), squamous cell is more serious because it is likely to spread (metastasize).
Can you pick off a basal cell carcinoma?
Yes, you might be able to pick this crusty lesion off with your fingers. But it would grow back. The right thing to do is see a dermatologist and have it removed.
Which is worse melanoma or carcinoma?
Melanomas are generally much more dangerous than carcinomas. Early detection helps with treatment in both cases and can be a key to dealing with the problem.