For the first time, a team led by researchers at the Icahn School of Medicine at Mount Sinai has proven that atopic dermatitis, also known as eczema, is an immune-driven (autoimmune) disease.
What autoimmune disease is associated with eczema?
Some primary immunodeficiency diseases are, however, associated with more severe eczema. These include WAS, Hyper-IgE Syndrome (HIES), IPEX syndrome, and certain forms of Severe Combined Immune Deficiency (SCID).
What are the underlying causes of eczema?
Common triggers include: irritants – such as soaps and detergents, including shampoo, washing-up liquid and bubble bath. environmental factors or allergens – such as cold and dry weather, dampness, and more specific things such as house dust mites, pet fur, pollen and moulds.
Can eczema be an autoimmune disease?
For the first time, a team led by researchers at the Icahn School of Medicine at Mount Sinai has proven that atopic dermatitis, also known as eczema, is an immune-driven (autoimmune) disease at the molecular level.
What organs does eczema affect?
Eczema affects your skin. The disease usually causes red, inflamed patches that are accompanied by intense itching. This reaction has been linked to a malfunction in the body’s immune system. People with eczema have lower levels of a particular cytokine (a protein), which helps their immune system function properly.
What food flares up eczema?
Some common foods that may trigger an eczema flare-up and could be removed from a diet include:
- citrus fruits.
- gluten or wheat.
- spices, such as vanilla, cloves, and cinnamon.
- some types of nuts.
Is eczema caused by an overactive immune system?
The most common type of eczema is actually a chronic disease called atopic dermatitis. The rashes on the surface are caused by an overactive immune system and an abnormal skin barrier.
Eczema has been linked to an increased risk of health conditions such as asthma, hay fever, food allergy, obesity and heart disease, Silverberg said.
Is eczema an autoimmune disease NHS?
An experimental drug that works by blocking the immune response that causes unsightly, itchy skin patches looks promising for treating atopic dermatitis (AD), also known as eczema.
Gut health and eczema
Recent studies have drawn a link between eczema and the health of the skin microbiome. However, there’s also evidence that gut health is a major factor in the cause and treatment of eczema. Research has shown that gut health is closely associated with the appearance of eczema in childhood.